According to a bombshell new study from the journal Neuropharmacology, psilocybin – a compound in psychedelic mushrooms – may be superior for treating clinical depression than conventional big pharma-produced antidepressant.
“Psilocybin-assisted therapy might mitigate depression by increasing emotional connection,” study author Leor Roseman explained in a PsyPost interview.antidepressant
SSRIs are the most common form of antidepressants doctors prescribe today. According to WebMD, SSRIs are designed to delay the brain’s serotonin absorption, causing more of the “happy” chemical to build up.
As Roseman mentioned, however, a common complaint with SSRIs is that they result in emotional blunting.
Researchers observed the incredible effects of psilocybin by subjecting 20 patients to brain scans as they took doses of it.
Doctors presented the patients — suffering from moderate to severe drug-resistant depression — faces showing various emotions. This was to test their ability to feel emotional connections.
Not only did the majority of patients report feeling lesser symptoms of depression as a result of the treatment – their brain scans also revealed heightened brain activity in response to the images. This signals a return to normative brain function missing in those suffering from depression.
“I believe that psychedelics hold a potential to cure deep psychological wounds, and I believe that by investigating their neuropsychopharmacological mechanism, we can learn to understand this potential,” Roseman told PsyPost.
The author added that the second round of testing will involve a control group, an SSRI group and increased time between treatment and observation.
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